Since early 2000 Lee Biosolutions, Inc has been producing Leukocytes in bulk 40 liter lots at a time for clients making urine controls. My R and D department headed by Dr. Drewe knowing I wanted new proteins isolated every 4-6 months indicated to me that there was a number of analytes that he could be isolate from the leukocyte extract we had on hand. So we embarked on a journey of purifying as many proteins that I felt we could market to researchers. Over time we had successfully isolated neutrophil proteins such as Cathepsin G , Lysozyme , Proteinase 3 , Lactoferrin and a green protein that was identified as Myeloperoxidase .
It wasn't until I read a study performed by the prestigous Cleveland Clinic Lerner Institute and published by The New England Journal of Medicine Prognostic Value of Myeloperoxidase in Patients with Chest Pain that I knew we potentially had a product that would have one of the greatest impacts on emergency room treatments, at least that was my opinion.
I read all that I could on Myeloperoxidase and current research being peformed. Have you ever had a gut feeling and just went with it? I had all the confidence in the world with my R and D Department. We developed specifications and began selling our first lot of Myeloperoxidase in 2003. Honestly our first lot of MPO bombed with Abbott labs with having a low RZ value in the low 5's, if you could believe it, of all companies. But that didn't deter me, it just proved to me that we were on the right track.
We now produce in bulk and have the capabilities of producing in gram quantities of MPO if required. We sell high quality Myeloperoxidase worldwide and soon you will find companies gaining FDA approval.
We also have isolated Myeloperoxidase Isoform C that is used Protein Crystallization Research. We have been able to separte out Eosinophil Peroxidase and Eosinophil Cationic Protein . These two products definitely are not easy to isolate but the number of requests we have had ensures us that they will be very busy isolating other analytes that we will be putting on the market later on this year.
Burton Lee
President
www.leebio.com
ps. I guess I should indicate that any reference to any organization does not constitute an endorsment of our products. It's that kind of world you guys.
